I am using the GDI+ assemblies 1_31 and Migradoc to create PDF's from multiple TIFF files.  I can view the PDF fine in other readers like PDF Complete and Nuance.  If the PDF is opened in Adobe Reader X, they get an "Insuficient Data for an image" message and none of the pages below are visible.
I read two different forum messages about this issue:
1) stated they used the GDI+ and it was fixed but I am already using that
2) stated they had to save each tiff as a seperate PDF page and them combine into a single PDF
Hoping someone out there has a better suggestion.  Please?
Below is the code I am using.  I uncompress a zip file.  Pull an *.asc file and open it.  That doc tells me what TIFF images belong in each grouping (single PDF file).
Code:
    
Imports MigraDoc.Rendering
Imports MigraDoc.DocumentObjectModel
Imports MigraDoc.RtfRendering
Imports ICSharpCode.SharpZipLib.Zip
Function ProcessIndexFile(ByVal myFileName As String, ByVal myFilePath As String) As Boolean
        Dim sFileReader As System.IO.StreamReader
        Dim sInputLine As String
        Dim sWholeLine As String
        Dim sDate As String
        Dim sControl As String
        Dim sRteNum As String
        Dim sDocNum As String
        Dim sImgFileName As String
        Dim hDocNum As String
        Dim hDate As String
        Dim hRteNum As String
        Dim fStart, fNewDoc As Boolean
        Dim myerr As String
        Dim myDoc As Document
        Dim myRend As PdfDocumentRenderer
        Dim mySec As Section
        Dim myImg As MigraDoc.DocumentObjectModel.Shapes.Image
        Dim myPS As MigraDoc.DocumentObjectModel.Orientation
        fStart = True
        fNewDoc = True
        myPS = Orientation.Landscape
        On Error GoTo errorhandler
        sFileReader = System.IO.File.OpenText(myFileName)   '*****Open File
        sInputLine = sFileReader.ReadLine
        Do Until sInputLine Is Nothing              '*****Loop Line by Line through file
            sWholeLine = sInputLine                 '*****Create variable to store line
            '******************************************************
            '*****Pull field values from line based on position
            '******************************************************
            sDate = Mid(sWholeLine, 1, 8)
            sDate = Replace(sDate, "/", "")
            sControl = Mid(sWholeLine, 18, 14)
            sRteNum = Mid(sWholeLine, 18, 6)
            sDocNum = Mid(sWholeLine, 29, 3)
            sImgFileName = Mid(sWholeLine, 63, 12)
            Debug.Print(sDate & Chr(9) & sControl & Chr(9) & sDocNum & Chr(9) & sImgFileName)
            If fStart = True Then                   '*****Sets comp for first line of file
                hRteNum = sRteNum
                hDocNum = sDocNum
                hDate = sDate
                fStart = False
            End If
            If sDocNum <> hDocNum Then
                '*****Document changed, write previous file and start new one
                MigraDoc.DocumentObjectModel.IO.DdlWriter.WriteToFile(myDoc, "MigraDoc.mdddl")
                myRend = New PdfDocumentRenderer(True, PdfSharp.Pdf.PdfFontEmbedding.Always)
                myRend.Document = myDoc
                myRend.RenderDocument()
                myRend.PdfDocument.Save("c:\Me\processed\Me_" & hDate & "_" & hRteNum & "_" & hDocNum & ".pdf")
                hDocNum = sDocNum
                fNewDoc = True
            End If
            If fNewDoc = True Then
                myDoc = New Document
                myDoc.Info.Title = "Process Documents"
                myDoc.Info.Subject = sControl
                myDoc.Info.Author = "Me"
                fNewDoc = False
            End If
            mySec = myDoc.AddSection
            myImg = mySec.AddImage(myFilePath & "\" & sImgFileName)
            myImg.LockAspectRatio = True
            myImg.Width = New Unit(7, UnitType.Inch)
            'mySec.AddPageBreak()
            sInputLine = sFileReader.ReadLine       '*****Go to next line in file
        Loop
        sFileReader.Close()
        ProcessIndexFile = True
        Exit Function
errorhandler:
        myerr = "This file did not parse correctly.  Please contact Me with error code and copy of zip file." & Chr(13) & Chr(13)
        MsgBox(myerr & Err.Number & ": " & Err.Description)
        Debug.Print(Err.Number & " - " & Err.Description & ": " & Err.Source)
        ProcessIndexFile = False
    End Function